Hypoxia Attenuates Colonic Innate Immune Response and Inhibits TLR4/NF-κB Signaling Pathway in Lipopolysaccharide-Induced Colonic Epithelial Injury Mice-Reference-Cited by-同舟云学术

Hypoxia Attenuates Colonic Innate Immune Response and Inhibits TLR4/NF-κB Signaling Pathway in Lipopolysaccharide-Induced Colonic Epithelial Injury Mice

Published:2023-01-01 Issue:1 Volume:43 Page:43-52
ISSN:1079-9907
Container-title:Journal of Interferon & Cytokine Research
language:en
Short-container-title:Journal of Interferon & Cytokine Research

Author:

Han Ying¹,Jia Ruhan¹,Zhang Jingxuan¹,Zhu Qinfang¹,Wang Xiaozhou¹,Ji Qiaorong²,Zhang Wei¹^ORCID

Affiliation:

1. Research Center for High Altitude Medicine, Key Laboratory of High Altitude Medicine (Ministry of Education), Key Laboratory of Application and Foundation for High Altitude Medicine Research in Qinghai Province (Qinghai-Utah Joint Research Key Lab for High Altitude Medicine), Qinghai University, Xining, China.

2. Department of Pathophysiology, School of Basic Medical Sciences, Xuzhou Medical University, Xuzhou, China.

Publisher

Mary Ann Liebert Inc

Subject

Virology,Cell Biology,Immunology

Link

https://www.liebertpub.com/doi/pdf/10.1089/jir.2022.0194

Reference67 articles.

1. Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function

2. TLR Signaling in the Gut in Health and Disease

3. Decreased Expression of Toll-Like Receptor-4 and MD-2 Correlates with Intestinal Epithelial Cell Protection Against Dysregulated Proinflammatory Gene Expression in Response to Bacterial Lipopolysaccharide

4. HIF-1α restricts NF-κB dependent gene expression to control innate immunity signals

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