Human Telomerase RNA Degradation by 2'-5'-Linked Oligoadenylate Antisense Chimeras in a Cell-Free System, Cultured Tumor Cells, and Murine Xenograft Models

Author:

Paranjape Jayashree M.1,Xu Da2,Kushner David M.34,Okicki James5,Lindner Daniel J.6,Cramer Hagen57,Silverman Robert H.1,Leaman Douglas W.2

Affiliation:

1. Departments of Cancer Biology and Immunology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH.

2. Department of Biological Sciences, University of Toledo, Toledo, OH 43606.

3. Department of Gynecology and Obstetrics, Cleveland Clinic Foundation, Cleveland, OH 44195.

4. Present address: University of Wisconsin Hospitals and Clinics, Madison, WI 53792.

5. Ridgeway Biosciences, Cleveland, OH 44195.

6. Taussig Cancer Center, Cleveland Clinic Foundation, Cleveland, OH 44195.

7. Present address: Girindus America, Cincinnati, OH 45215.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

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