Non-Antibiotic Approaches to Infection that Preserve the Microbiome in Critically Ill Patients
Author:
Affiliation:
1. Barnes Jewish Hospital, St. Louis, Missouri, USA.
Publisher
Mary Ann Liebert Inc
Subject
Infectious Diseases,Microbiology (medical),Surgery
Link
https://www.liebertpub.com/doi/pdf/10.1089/sur.2023.020
Reference50 articles.
1. The role of the microbiota in the management of intensive care patients
2. Development of SYN-004, an oral beta-lactamase treatment to protect the gut microbiome from antibiotic-mediated damage and prevent Clostridium difficile infection
3. Nonclinical Safety Assessment of SYN-004
4. Use of ribaxamase (SYN-004), a β-lactamase, to prevent Clostridium difficile infection in β-lactam-treated patients: a double-blind, phase 2b, randomised placebo-controlled trial
5. Tolerability and Pharmacokinetics of SYN-004, an Orally Administered β-Lactamase for the Prevention of Clostridium difficile-Associated Disease and Antibiotic-Associated Diarrhea, in Two Phase 1 Studies
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