K1-70 — A Thyrotropin Receptor Antagonist with Therapeutic Potential in Graves' Disease, Thyroid Eye Disease, and Differentiated Thyroid Cancer
Author:
Affiliation:
1. Department of Endocrinology and Diabetes, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia
2. Population Health Department, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
Publisher
Mary Ann Liebert Inc
Subject
General Engineering
Link
https://www.liebertpub.com/doi/pdf/10.1089/ct.2021%3B33.433-436
Reference8 articles.
1. In vivo effects of a human thyroid-stimulating monoclonal autoantibody (M22) and a human thyroid-blocking autoantibody (K1-70)
2. ORIGINAL ARTICLE: Monoclonal autoantibodies to the TSH receptor, one with stimulating activity and one with blocking activity, obtained from the same blood sample
3. Blocking the TSH receptor with K1-70™ in a patient with follicular thyroid cancer, Graves' disease and Graves' ophthalmopathy
4. When Will Thyrotropin Receptor Antagonists and Inverse Thyrotropin Receptor Agonists Become Available for Clinical Use?
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