Preclinical Evaluation of Targeting the Nrf2 Pathway by Triterpenoids (CDDO-Im and CDDO-Me) for Protection from LPS-Induced Inflammatory Response and Reactive Oxygen Species in Human Peripheral Blood Mononuclear Cells and Neutrophils-Reference-Cited by-同舟云学术

Preclinical Evaluation of Targeting the Nrf2 Pathway by Triterpenoids (CDDO-Im and CDDO-Me) for Protection from LPS-Induced Inflammatory Response and Reactive Oxygen Species in Human Peripheral Blood Mononuclear Cells and Neutrophils

Published:2007-11 Issue:11 Volume:9 Page:1963-1970
ISSN:1523-0864
Container-title:Antioxidants & Redox Signaling
language:en
Short-container-title:Antioxidants & Redox Signaling

Author:

Thimmulappa Rajesh K.¹,Fuchs Ralph J.²,Malhotra Deepti¹,Scollick Catherine¹,Traore Kassim¹,Bream Jay H.³,Trush Michael A.¹,Liby Karen T.⁴,Sporn Michael B.⁴,Kensler Thomas W.¹,Biswal Shyam¹⁵

Affiliation:

1. Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland.

2. Department of Anesthesiology and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland.

3. Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland.

4. Department of Pharmacology and Toxicology, Dartmouth Medical School Hanover, New Hampshire.

5. Division of Pulmonary and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland.

Publisher

Mary Ann Liebert Inc

Subject

Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry,Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry

Link

http://www.liebertpub.com/doi/pdf/10.1089/ars.2007.1745

Reference35 articles.

1. Nuclear Factor–κB and Its Role in Sepsis‐Associated Organ Failure

2. Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care

3. Involvement of Reactive Oxygen Species in Toll-Like Receptor 4-Dependent Activation of NF-κB

4. Role of NRF2 in Protection Against Hyperoxic Lung Injury in Mice

5. The transcription factor NRF2 protects against pulmonary fibrosis

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