The New Self-Inactivating Lentiviral Vector for Thalassemia Gene Therapy Combining Two HPFH Activating Elements Corrects Human Thalassemic Hematopoietic Stem Cells-Reference-Cited by-同舟云学术

The New Self-Inactivating Lentiviral Vector for Thalassemia Gene Therapy Combining Two HPFH Activating Elements Corrects Human Thalassemic Hematopoietic Stem Cells

Published:2012-01 Issue:1 Volume:23 Page:15-31
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Papanikolaou Eleni¹²,Georgomanoli Maria¹²,Stamateris Evangelos¹²,Panetsos Fottes³,Karagiorga Markisia⁴,Tsaftaridis Panagiotis⁵,Graphakos Stelios⁶,Anagnou Nicholas P.¹²

Affiliation:

1. Laboratory of Cell and Gene Therapy, Center for Basic Research, Biomedical Research Foundation of the Academy of Athens (BRFAA), 11527 Athens, Greece.

2. Laboratory of Biology, University of Athens School of Medicine, 11527 Athens, Greece.

3. Biodiagnostics, 11526 Athens, Greece.

4. Thalassemia Unit, Saint Sophia Children's Hospital, 11527 Athens, Greece.

5. National Center for Thalassemia, World Health Organization Collaborating Center for the Community Control of Hereditary Diseases, Laikon General Hospital, 11527 Athens, Greece.

6. Bone Marrow Transplantation Unit, University of Athens School of Medicine, Saint Sophia Children's Hospital, 11527 Athens, Greece.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.2011.048

Reference47 articles.

1. Sequences Located 3′ to the Breakpoint of the Hereditary Persistence of Fetal Hemoglobin-3 Deletion Exhibit Enhancer Activity and Can Modify the Developmental Expression of the Human Fetal Aγ-Globin Gene in Transgenic Mice

2. Improved Human β-globin Expression from Self-inactivating Lentiviral Vectors Carrying the Chicken Hypersensitive Site-4 (cHS4) Insulator Element

3. The 3′ Region of the Chicken Hypersensitive Site-4 Insulator Has Properties Similar to Its Core and Is Required for Full Insulator Activity

4. Genetic correction of sickle cell disease: Insights using transgenic mouse models

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