Characterization of Anti-HIV Activity Mediated by R88-APOBEC3G Mutant Fusion Proteins in CD4+T cells, Peripheral Blood Mononuclear Cells, and Macrophages-Reference-Cited by-同舟云学术

Characterization of Anti-HIV Activity Mediated by R88-APOBEC3G Mutant Fusion Proteins in CD4+T cells, Peripheral Blood Mononuclear Cells, and Macrophages

Published:2011-10 Issue:10 Volume:22 Page:1225-1237
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Ao Zhujun¹,Wang Xiaoxia¹,Bello Alexander²,Jayappa Kallesh Danappa¹,Yu Zhe¹,Fowke Keith²,He Xinying³,Chen Xi⁴,Li Junhua⁴,Kobinger Gary²⁵,Yao Xiaojian¹²

Affiliation:

1. Laboratory of Molecular Human Retrovirology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.

2. Department of Medical Microbiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.

3. Department of Histology, Montreal Children's Hospital Research Institute and McGill University Health Center, Montreal, QC H3Z 2Z3, Canada.

4. Hunan Provincial Center For Disease Control and Prevention, 450 Furong Zhong Lu Yiduan of Changsha 410005, China.

5. Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winipeg, MB R3E 3R2, Canada.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.2010.012

Reference65 articles.

1. APOBEC3G Is Incorporated into Virus-like Particles by a Direct Interaction with HIV-1 Gag Nucleocapsid Protein

2. Contribution of the C-terminal tri-lysine regions of human immunodeficiency virus type 1 integrase for efficient reverse transcription and viral DNA nuclear import

3. Interaction of Human Immunodeficiency Virus Type 1 Integrase with Cellular Nuclear Import Receptor Importin 7 and Its Impact on Viral Replication

4. Importin α3 Interacts with HIV-1 Integrase and Contributes to HIV-1 Nuclear Import and Replication

5. Vpr14-88-Apobec3G Fusion Protein Is Efficiently Incorporated into Vif-Positive HIV-1 Particles and Inhibits Viral Infection

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