Gammaretroviral Vector Integration Occurs Overwhelmingly Within and Near DNase Hypersensitive Sites-Reference-Cited by-同舟云学术

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Gammaretroviral Vector Integration Occurs Overwhelmingly Within and Near DNase Hypersensitive Sites

Published:2012-02 Issue:2 Volume:23 Page:231-237
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Liu Mingdong¹,Li Chang Long¹,Stamatoyannopoulos George¹,Dorschner Michael O.²,Humbert Richard²,Stamatoyannopoulos John A.²,Emery David W.¹³

Affiliation:

1. Department of Medicine, Division of Medical Genetics, University of Washington, Seattle, Washington.

2. Department of Genome Sciences, University of Washington, Seattle, Washington.

3. Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, Washington.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.2010.177

Reference33 articles.

1. Binding of disparate transcriptional activators to nucleosomal DNA is inherently cooperative

2. Integration Bias of Gammaretrovirus Vectors following Transduction and Growth of Primary Mouse Hematopoietic Progenitor Cells with and without Selection

3. Mutagenesis and Oncogenesis by Chromosomal Insertion of Gene Transfer Vectors

4. Selection of Target Sites for Mobile DNA Integration in the Human Genome

5. The insulation of genes from external enhancers and silencing chromatin

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Evidence for the in vivo safety of insulated foamy viral vectors;Gene Therapy;2016-12-26

2. A comparison of foamy and lentiviral vector genotoxicity in SCID-repopulating cells shows foamy vectors are less prone to clonal dominance;Molecular Therapy - Methods & Clinical Development;2016

3. Ectopic expression of HOXC6 blocks myeloid differentiation and predisposes to malignant transformation;Experimental Hematology;2014-02

4. MLV integration site selection is driven by strong enhancers and active promoters;Nucleic Acids Research;2014-01-23

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