Genetically Modified Donor Leukocyte Transfusion and Graft-Versus-Leukemia Effect After Allogeneic Stem Cell Transplantation-Reference-Cited by-同舟云学术

Genetically Modified Donor Leukocyte Transfusion and Graft-Versus-Leukemia Effect After Allogeneic Stem Cell Transplantation

Published:2011-07 Issue:7 Volume:22 Page:829-841
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Borchers Sylvia¹,Provasi Elena²,Silvani Anna³,Radrizzani Marina³,Benati Claudia³,Dammann Elke¹,Krons Annika⁴,Kontsendorn Julia¹,Schmidtke Joerg⁵,Kuehnau Wolfgang⁵,von Neuhoff Nils⁶,Stadler Michael¹,Ciceri Fabio²,Bonini Chiara²,Ganser Arnold¹,Hertenstein Bernd¹⁴,Weissinger Eva M.¹

Affiliation:

1. Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover 30625, Germany.

2. Cancer Immunotherapy and Gene Therapy Program, San Raffaele Hospital, Milan 20123, Italy.

3. MolMed, Milan 20123, Italy.

4. Mosaiques Diagnostics, Hannover 30625, Germany.

5. Institute of Human Genetics, Hannover Medical School, Hannover 30625, Germany.

6. Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover 30625, Germany.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.2010.162

Reference42 articles.

1. Early reconstitution of the T-cell repertoire after non-myeloablative peripheral blood stem cell transplantation is from post-thymic T-cell expansion and is unaffected by graft-versus-host disease or mixed chimaerism

2. T cell-depleted bone marrow transplantation and delayed T cell add-back to control acute GVHD and conserve a graft-versus-leukemia effect

3. Suicide gene therapy of graft-versus-host disease induced by central memory human T lymphocytes

4. Suicide Gene Transduced T-cells for the Regulation of the Graft-versus-Leukemia Effect

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