Thermosensitivity of the Reverse Transcription Process as an Inactivation Mechanism of Lentiviral Vectors-Reference-Cited by-同舟云学术

Thermosensitivity of the Reverse Transcription Process as an Inactivation Mechanism of Lentiviral Vectors

Published:2009-10 Issue:10 Volume:20 Page:1168-1176
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Carmo M.¹,Dias J.D.¹,Panet A.²,Coroadinha A.S.¹,Carrondo M.J.T.¹³,Alves P.M.¹,Cruz P.E.¹⁴

Affiliation:

1. Instituto de Tecnologia Química e Biológica-Universidade Nova de Lisboa/Instituto de Biologia Experimental e Tecnológica (ITQB-UNL/IBET), P-2781-901 Oeiras, Portugal.

2. Institute of Medical Research, The Hebrew University-Hadassah Medical School Ein Kerem, 91120 Jerusalem, Israel.

3. Faculdade de Ciencias e Tecnologia-Universidade Nova de Lisboa (FCT-UNL), P-2825 Monte da Caparica, Portugal.

4. ECBio, P-2781-901 Oeiras, Portugal.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.2009.068

Reference34 articles.

1. HIV-1 reverse transcription initiation: A potential target for novel antivirals?

2. Lentiviral vectors for cancer immunotherapy: transforming infectious particles into therapeutics

3. Inducible Packaging Cells for Large-scale Production of Lentiviral Vectors in Serum-free Suspension Culture

4. Quantitation of MLV-based retroviral vectors using real-time RT-PCR

5. From retroviral vector production to gene transfer: spontaneous inactivation is caused by loss of reverse transcription capacity

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