The Green and Efficient One-pot Synthesis of Tetrahydrobenzo[b]pyran Derivatives
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Published:2023-10-11
Issue:
Volume:
Page:148-152
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ISSN:1984-6428
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Container-title:Orbital: The Electronic Journal of Chemistry
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language:
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Short-container-title:Orbital: Electron. J. Chem.
Author:
Ankush Bhaskar P.,
Shitole Balasaheb V.,
Shitole Nana V.ORCID
Abstract
Glutamic acid is used as an efficient organocatalyst for one-pot synthesis of tetrahydrobenzo [b]pyran via condensation of an aromatic aldehyde, dimedone and malononitrile in ethanol: water (1:4) as solvent at reflux temperature. The short reaction time, cleaner reaction, and easy workup make this protocol practical and economically attractive.
Publisher
Instituto de Quimica - Univ. Federal do Mato Grosso do Sul
Subject
Materials Science (miscellaneous),General Chemical Engineering,General Chemistry