The antiradical activity of plant extracts and healthful preventive combinations of these exrtacts with the phospholipid complex

Author:

Baranova V.S.1,Rusina I.F.2,Guseva D.A.3,Prozorovskaya N.N.1,Ipatova O.M.1,Kasaikina O.T.2

Affiliation:

1. Orekhovich Institute of Biomedical Chemistry, Russian Medical Academy of Sciences

2. Semenov Institute of Chemical Physics, Russian Academy of Sciences

3. Moscow State University of Technique and Control

Abstract

Using the chemiluminescence method, the effective concentration of antioxidants (AO) and its reactivity toward peroxyl radicals (ARA, the k7 constant) have been measured for 13 plant extracts. In fact all extracts demonstrated ARA higher than ionol. Larix dahurica, Hypericum perforatum, Potentilla fruticosa, Aronia melanocarpa and Rhaponticum carthamoides extracts showed the highest values of ARA. The combinations Aronia + Raponticum extracts; Larix + Hibiscus extracts; Schizandra +Aronia extracts were synergistic (the synergism effect β of 38%, 33% and 22%). Apparently this phenomenon is the result of the synergistic interaction between compounds present in plant extracts. The Phospholipid complex - Lipoid S40, lacting any antioxidant effect alone, showed a potent synergistic effect with Aronia extract (β = 60%), Silybum extract (β = 41%). Clinical trials demonstrated, that combinations "Lipoid + Aronia extract", "Lipoid + Larix extract + Hibiscus extract", "Lipoid + Silybum extract", "Lipoid + Q10 + Rosa majalis extract" may be used as an additional component in the medicinal treatment, or as an individual prophylactic agent.

Publisher

Institute of Biochemistry

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. A Comprehensive Overview of Hibiscus rosa-sinensis L.: Its Ethnobotanical Uses, Phytochemistry, Therapeutic Uses, Pharmacological Activities, and Toxicology;Endocrine, Metabolic & Immune Disorders - Drug Targets;2024-01

2. Pharmacognostical and phytochemical studies of Iraqi Hibiscus rosa-sinensis;THE 7TH INTERNATIONAL CONFERENCE ON APPLIED SCIENCE AND TECHNOLOGY (ICAST 2019);2019

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