Blood metabolome analysis for creating a digital image of a healthy person

Author:

Trifonova O.P.1,Balashova E.E.1,Maslov D.L.1,Grigoriev A.I.2,Lisitsa A.V.1,Ponomarenko E.A.1,Archakov A.I.1

Affiliation:

1. Institute of Biomedical Chemistry, Moscow, Russia

2. Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Russia

Abstract

In the frame of the work, data on the implementation of metabolomics tests in medicine have been systematized. Based on the obtained data, a set of protocols was proposed, the sequential realization of which makes it possible to conduct a blood metabolome analysis for medical purposes. Using this analysis and the number of blood samples from healthy volunteers, a prototype of a healthy person's metabolomic image has been developed; it allows visually and digitally to assess the compliance of the human blood metabolome with the norm. At the same time, 99% of the metabolic processes reflected in the blood plasma are estimated. If abnormalities are detected, the metabolomic image allows to get the value of these deviations of metabolic processes in digital terms.

Publisher

Institute of Biochemistry

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

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