Affiliation:
1. Institute of Experimental Medicine
2. Saint Petersburg Pasteur Institute; Saint Petersburg State University
Abstract
Currently, there is an urgent question of optimizing the treatment of stomach diseases associated with Helicobacter pylori, due to the increasing resistance of the pathogen to antibiotics and the presence of side effects of standard therapy. To optimize it, it is proposed to use probiotics as an additional or monotherapy. The review presents the results of studies of anti-helicobacter activity by in vitro and in vivo systems, as well as an assessment of the clinical effectiveness of various probiotic strains of microorganisms in eradication therapy. Several mechanisms of action of probiotics in the treatment of HP-related diseases are discussed. The problems and prospects of using personalized therapy of helicobacteriosis with probiotics and autoprobiotics, based on strains obtained from the gastrointestinal tract, are indicated.
Publisher
LLC Global Media Technology
Reference95 articles.
1. Mezmale L., Coelho L. G., Bordin D., Leja M. Review: Epidemiology of Helicobacter pylori. Helicobacter. 2020;25(S1):6-10. doi: 10.1111/hel.12734
2. Zamani M., Ebrahimtabar F., Zamani V., et al. Systematic review with meta-analysis: the worldwide prevalence of Helicobacter pylori infection. Aliment Pharmacol Ther. 2018;47(7):868-76. doi: 10.1111/apt.14561
3. Gladyshev N.S., Molostova A. S., Svarval A. V., et al. Gastric and extragastric diseases associated with Helicobacter pylori infection. Health-the base of human potential: problems and ways to solve them. 2019;1(6):14. (in Russ.)
4. Chernin V.V., Bondarenko V. M., Chervinets V. M., et al. [Helicobacter pylori as an integral part of the microbiocenosis of the mucous microflora of the esophagogastroduodenal zone in health and disease]. Eksp Klin Gastroenterol. 2001; (8):66-72. (in Russ.)
5. Tsimmerman Ya. S. Has the discovery of Helicobacter pylori actually made a revolution in gastroenterology?. Klinicheskaya Meditsina. 2013;91(8):13-21. (in Russ.)
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