Polymorphisms of cytokine genes in the mechanisms of development of inflammatory and ultrasonic gastric damage

Abstract

To date, sufficiently reliable data have been accumulated on the involvement of various cytokine genes, the products of which are directly involved in the regulation of the immune response in inflammatory processes of the gastric mucosa. However, among these works, studies devoted to the genetic mechanisms of the formation of inflammatory and ulcerative lesions of the stomach are few in number, and the data obtained are contradictory. Meanwhile, the identification of predisposing factors that can modulate the progression of the inflammatory process leading to the development of stomach ulcers is very important in terms of developing their early prognostic criteria, and, at the same time, preventive and therapeutic strategies.