Neurogenic-genetic theory of etiology peptic ulcer disease

Author:

Ivanov L. N.1,Kolotilova M. L.2ORCID

Affiliation:

1. Chuvash State University n. a. I. N. Ulyanov

2. I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation

Abstract

The purpose of the study. Improvement of the author's Neurogenic-genetic theory of the etiology of the pathogenesis of peptic ulcer disease. Materials and methods: To develop the author's view on the etiology and pathogenesis of peptic ulcer disease, about 50 different publications were processed and the results of their own research were analyzed. Results. Consequently, the neurogenic-genetic theory of the etiology and pathogenesis of gastric and duodenal ulcer very optimally explains the cause-and-effect relationships in a patient with ULCER, allowing for variants of the prevalence of neurosis factor or local genetic factors in one case or another. However, another thing is obvious, that only a combination of a neurogenic factor with a genetically altered reactivity of the gastroduodenal system (the presence of a target organ) causes the chronic ulcers. The theory of peptic ulcer disease developed by us, as a disease related to psychosomatic pathology, allows us to develop effective therapy, including drugs with a psychocorregulating effect.

Publisher

LLC Global Media Technology

Reference39 articles.

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2. Ivashkin V.T., Rapoport S.I. The decision of the Board of the Ministry of Health is the path to solving current problems of gastroenterology. Ross. J Gastroenterology, Hepatology, Coloproctology. (Appendix 23). 2004;(14):5-30. (in Russ.)@@ Ivashkin V.T., Rapoport S.I. Reshenie kollegii MZ - put' k resheniyu aktual'nykh zadach gastroenterologii. Ros. zhurn. Gastroenterologii, Gepatologii, Koloproktologii. (pril. 23). 2004;(14):5-30.

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4. Soshina A.A., Sergeeva V.V., Zinyaeva T.V. Features of the clinical picture and prognosis in patients examined at the Bureau of Medical and Social Expertise in connection with peptic ulcer of the stomach and duodenum. Kaz.medical journal. 2013;(94)1: 124-127. (in Russ.)@@ Soshina A.A., Sergeeva V.V., Zinyaeva T.V. Osobennosti klinicheskoi kartiny i prognoz u patsientov, osvidetel'stvovannykh v byuro mediko-sotsial'noi ekspertizy v svyazi s yazvennoi bolezn'yu zheludka i dvenadtsatiperstnoi kishki. Kaz.med.zhurnal. 2013;(94)1: 124-127.

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