Endoscopic and morphological changes in eosinophilic enteritis in children: current concepts and own observations

Author:

Budkina T. N.1ORCID,Lokhmatov M. M.2ORCID,Makarova S. G.3ORCID,Fisenko A. P.1ORCID,Khavkin A. I.4ORCID,Vyazankina S. S.1ORCID,Oldakovsky V. I.1ORCID,Tupylenko A. V.1ORCID,Korolev G. A.1ORCID,Kulikov K. A.1ORCID

Affiliation:

1. National Medical Research Center for Children’s Health

2. National Medical Research Center for Children’s Health; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)

3. National Medical Research Center for Children’s Health; M.V. Lomonosov Moscow State University

4. Research Clinical Institute of Childhood of the Ministry of Health of the Moscow Region; Belgorod State Research University. Ministry of Science and Higher Education of the Russian Federation

Abstract

Eosinophilic enteritis (EoEn) is a rare disease, the key diagnostic method for which is upper endoscopy with biopsies and histological examination. The article presents criteria of the diagnosis of EoEn, the range of detected endoscopic (including video capsule and balloon-assisted enteroscopy) and morphological lesions; emphasis is placed on the specific endoscopic sign of this pathology. Clinical examples with our own endoscopic examinations in children with EoEn are also presented. The article will improve the awareness of gastroenterologists and endoscopists about EoEn for timely diagnosis of the disease and treatment.

Publisher

LLC Global Media Technology

Reference17 articles.

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2. Jensen E.T., Martin C.F., Kappelman M.D. et al. Prevalence of Eosinophilic Gastritis, Gastroenteritis, and Colitis: Estimates From a National Administrative Database. J Pediatr Gastroenterol Nutr. 2016;62(1):36-42.

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4. Makarova S. G., Lavrova T. E., Novik G. A. Non-IgE-mediated gastrointestinal food allergy in children. Diagnostics, differential diagnostics, tactics of diet therapy. Lechaschi Vrach. 2023; 6 (26): 20-28. (in Russ.) doi: 10.51793/OS.2023.26.6.003.@@ Makarova S.G., Lavrova T.E., Novik G.A. Ne-IgE-oposredovannaya gastrointestinal'naya pishchevaya allergiya u detei. Diagnostika, differentsial'naya diagnostika, taktika dietoterapii. Lechashchii vrach 2023; 6 (26): 20-28. doi: 10.51793/OS.2023.26.6.003.

5. Campora M., Mastracci L., Carlin L. et al. Pathologist’s approach to paediatric and neonatal eosinophilic gastrointestinal disorders. Pathologica. 2022 Feb;114(1):79-88. doi: 10.32074/1591-951X-734.

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