Affiliation:
1. Bashkir State Medical University
Abstract
Aim was to study the prevalence of gastrointestinal tract pathology and the state of intestinal biocenosis among bronchial asthma patients.Materials and methods: 93 patients with asthma in the exacerbation stage who had diseases of the gastrointestinal tract were examined. Instrumental, immunological, bacterial studies of the respiratory and digestive organs were carried out.The results of our study indicate a relationship between the development of bronchial asthma and gastrointestinal pathology due to negative environmental effects, stress, glucocorticosteroid therapy, changes in general and local protective reactions against a background of a chronic disease involving organ barriers with an autoimmune pathogenesis mechanism in the pathological process.
Publisher
LLC Global Media Technology
Subject
Gastroenterology,Hepatology
Reference11 articles.
1. Brodskaya O.N. [Bronchial asthma and GERD: topical issues of diagnosis and treatment]. Astma i allergiya = Asthma and Allergy. 2016;(2): 11–14. (In Russ)
2. Yurenev G.L., Samsonov A. A., Yureneva- Tkhorzhevskaya T.V., Maev I. V. [Broncho- obstructive syndrome in patients with gastroesophageal reflux disease: extraesophageal manifestation of the disease or bronchial asthma?]. Consilium Medicum. 2014;16(8):33–38. (in Russ.)
3. Steppuhn H., Langen U., Scheidt- Nave C., Keil T. Major comorbid conditions in asthma and association with asthma- related hospitalizations and emergency department admissions in adults: results from the German National Health Telephone Interview Survey (GEDA) 2010. BMC Pulm Med. 2013 Jul 12;13:46. doi: 10.1186/1471-2466-13-46.
4. Abrosimov V.N., Ponomareva I. B., Nizov A. A., Solodun M. V. On respiratory manifestations of gastroesophageal reflux disease. Terapevticheskii arkhiv. 2018;90(8): 131–136. (In Russ) doi: 10.26442/terarkh2018908131-136.
5. Fedorova S.O., Kozlova N. M. Gastroesophageal reflux disease associated with diseases of the respiratory tract. Acta Biomedica Scientifica. 2018;3(3):103–107. (In Russ.) doi: 10.29413/ABS.2018-3.3.16.