Antibiotics: the triumph of civilization and its other side

Author:

Osadchuk M. A.1ORCID,Osadchuk M. M.2ORCID,Mironova E. D.1ORCID

Affiliation:

1. Federal State Autonomous Educational Institution of Higher Education I. M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)

2. Moscow State Budgetary Healthcare Institution “City Polyclinic No. 52 of the Moscow Department of Health”

Abstract

The synthesis of antibacterial drugs and their subsequent use in clinical practice contributed to saving a huge number of people’s lives in the global space. At the same time, they can cause significant harm, including Clostridium difficile infections, in the formation of antibiotic resistance and changes in the human microbiome, the consequences of which have yet to be assessed. Antibiotic management programs are becoming more and more commonplace in modern clinical practice, requiring extensive knowledge based on clinical, genomic and laboratory data. Increasing evidence suggests a role for antibiotics in the manifestation of allergic, inflammatory, metabolic, and functional diseases. On the other hand, there is more and more data on the role of antimicrobial drugs in cancer prevention and treatment of viral diseases.

Publisher

LLC Global Media Technology

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