The concept of the development of inflammatory bowel diseases as a consequence of intestinal metabolic dysbiosis

Author:

Tarasova L. V.1,Tsyganova Yu. V.1ORCID,Pavlova S. I.1,Kucherova N. Y.1

Affiliation:

1. Chuvash State University named after I. N. Ulyanova

Abstract

The article discusses the high relevance of the problem of inflammatory bowel diseases (IBD). First of all, attention is drawn to the annual increase in the incidence of ulcerative colitis and Crohn’s disease. Factors that can influence the development of IBD are assessed. A diagram of the pathogenetic cascade of dysbiotic disorders is presented, manifested by an increase in the blood serum of metabolic products of the intestinal microflora, microvascular, metabolic and immune changes leading to the triggering of inflammation in the intestinal wall.

Publisher

LLC Global Media Technology

Reference42 articles.

1. Knyazev O.V., Shkurko T. V., Fadeyeva N. A., Bakulin I. G., Bordin D. S. Epidemiology of chronic inflammatory bowel disease. Yesterday, today, tomorrow. Experimental and Clinical Gastroenterology. 2017;(3):4-12. (In Russ.)@@ Knyazev O. V., Shkurko T. V., Fadeeva N. A., Bakulin I. G., Bordin D. S. Epidemiologiya khronicheskikh vospalitel'nykh zabolevanii kishechnika. Vchera, segodnya, zavtra. Eksperimental'naya i klinicheskaya gastroenterologiya. 2017;(3):4-12.

2. Veselov A.V., Belousova E. A., Bakulin I. G. [et al.]. Assessment of the economic burden and the current state of the organization of drug provision for patients with immunoinflammatory diseases (using the example of ulcerative colitis and Crohn’s disease) in the Russian Federation. Problems of social hygiene, health care and history of medicine. 2020;28(special issue):1137-1145. (in Russ.) doi: 10.32687/0869-866X-2020-28-s2-1137-1145E.@@ Veselov A. V., Belousova E. A., Bakulin I. G. i soavt. Otsenka ekonomicheskogo bremeni i tekushchego sostoyaniya organizatsii lekarstvennogo obespecheniya patsientov s immunovospalitel'nymi zabolevaniyami (na primere yazvennogo kolita i bolezni Krona) v Rossiiskoi Federatsii. Problemy sotsial'noi gigieny, zdravookhraneniya i istorii meditsiny. 2020;28(spetsvypusk):1137-1145. doi: 10.32687/0869-866X-2020-28-s2-1137-1145E.

3. Valuyskikh Yu., Svetlova I. O., Kurilovich S. A. et al. Clinical and genetic aspects of inflammatory bowel diseases.Russian Journal of Gastroenterology, Hepatology and Coloproctology. 2008; 18(6): 68-74. (in Russ.)@@ Valuiskikh Yu., Svetlova I. O., Kurilovich S. A. i soavt. Kliniko-geneticheskie aspekty vospalitel'nykh zabolevanii kishechnika. Rossiiskii zhurnal gastroenterologii, gepatologii i koloproktologii. 2008; 18(6): 68-74.

4. Syed U., Subramanian A., Wraith D. C. et al. Incidence of immune-mediated inflammatory diseases following COVID-19: a matched cohort study in UK primary care. BMC Med. 2023;(21):363. doi: 10.1186/s12916-023-03049-5.

5. Räisänen L., Viljakainen H., Kolho K-L. Exposure to proton pump inhibitors is associated with the development of pediatric autoimmune diseases. Front. Pediatr.2023;(11):1157547. doi: 10.3389/fped. 2023.1157547.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3