Targeted therapy in oncology

Author:

Semenkin A. A.1ORCID,Sapronenko V. S.1ORCID,Loginova E. N.1ORCID,Nadey E. V.1ORCID

Affiliation:

1. Omsk State Medical University

Abstract

The aim of the review is to highlight the principle of action, effectiveness and prospects for the development of targeted therapy in the treatment of patients with malignant neoplasms based on recent clinical studies. Thanks to the active study of tumor biology, specific target molecules have been discovered and it has become possible to target tumor cells with targeted drugs. Today, targeted drugs are used in the treatment of malignant tumors of various organs and continue to demonstrate their effectiveness, improve overall survival and progression-free time, compared with previous standards of treatment.

Publisher

LLC Global Media Technology

Subject

Gastroenterology,Hepatology

Reference35 articles.

1. Ferlay J., Ervik M., Lam F., et al. Global Cancer Observatory: Cancer Today. Lyon: International Agency for Research on Cancer; 2020. Available at: https://gco.iarc.fr/today (Accessed: 27 March 2022)

2. Smelov P. A., Nikitina S.YU. (red) Healthcare in Russia. 2021. Moscow. Stat.sb./Rosstat Publ., 2021. (In Russ.) @@Smelov P. A., Nikitina S. Yu. (red) Zdravookhranenie v Rossii. 2021. - Moskva: Stat.sb./Rosstat, 2021.

3. Hanahan D., Weinberg R. A. The hallmarks of cancer. Cell. 2000;100(1):57-70. doi:10.1016/s0092-8674(00)81683-9

4. Hanahan D., Weinberg R. A. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646-674. doi:10.1016/j.cell.2011.02.013

5. Tyulyandin S. A. Targeted therapy: Twenty years of success and failures. Practical oncology. 2019;4(20):274-288. (In Russ.) doi:10.31917/2004274 @@Tyulyandin S. A. Targetnaya terapiya: dvadtsat' let uspekhov i porazhenii. Prakticheskaya onkologiya. 2019;4(20):274-288. doi:10.31917/2004274

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3