The application of proteomics to diabetes-Reference-Cited by-同舟云学术

The application of proteomics to diabetes

Published:2005-05 Issue:2 Volume:2 Page:54-60
ISSN:1479-1641
Container-title:Diabetes and Vascular Disease Research
language:en
Short-container-title:Diabetes and Vascular Disease Research

Author:

Scott Eleanor M¹,Carter Angela M¹,Findlay John BC²

Affiliation:

1. Academic Unit of Molecular Vascular Medicine, The LIGHT Laboratories, Clarendon Way, University of Leeds, Leeds, LS2 9JT, UK

2. Department of Biochemistry, Leeds University, Leeds, UK

Abstract

Proteomics is the investigation of all the proteins and their various modifications making up a system, be that a cell, tissue or organism. The techniques involved in proteomics allow the global screening of complex samples of proteins and provide qualitative and quantitative evidence of altered protein expression. This lends itself to the investigation of the molecular mechanisms underpinning disease processes and the effects of treatment. This review describes the main techniques of proteomics and how they have begun to be applied to diabetes research.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine,Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

http://journals.sagepub.com/doi/pdf/10.3132/dvdr.2005.009

Reference46 articles.

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2. IRS proteins and the common path to diabetes

3. The burden of type 2 diabetes: are we doing enough?

4. The central role of fat and effect of peroxisome proliferator-activated receptor–γ on progression of insulin resistance and cardiovascular disease

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