Residual Renal Function: A Double-Edged Sword

Abstract

<b><i>Introduction:</i></b> Nephrotic syndrome may persist despite end-stage kidney disease and result in dyslipidaemia, thrombosis and a significantly increased cardiovascular risk. Treatment of refractory nephrotic syndrome includes surgical bilateral nephrectomy, renal artery embolization and pharmacologic nephrectomy. <b><i>Case Presentation:</i></b> We present a case of a haemodialysis patient with refractory nephrotic syndrome who underwent pharmacologic nephrectomy. The procedure decreased the patient‘s cardiovascular risk and enabled the patient to become a candidate for kidney transplantation. <b><i>Conclusion:</i></b> In certain situations residual renal function may be harmful. In such instances, nephrectomy should be considered. Pharmacologic nephrectomy using nephrotoxic drugs is a non-invasive approach with least potential complications.