Recurrent Fever due to Helicobacter cinaedi Infection during R-CHOP Chemotherapy in Diffuse Large B-Cell Lymphoma: Case Report and Literature Review

Abstract

Fever due to <i>Helicobacter cinaedi</i> bacteremia under chemotherapy has not been widely recognized among clinicians. We experienced a 72-year-old man with diffuse large B-cell lymphoma, who was complicated with <i>H. cinaedi</i> bacteremia-induced fever under R-CHOP chemotherapy. We summarized 6 cases including ours, suggesting that fever without neutropenia developing around day 6 from starting chemotherapy is a possible symptom caused by <i>H. cinaedi</i> bacteremia. We should discriminate fever due to <i>H. cinaedi</i> bacteremia if fever emerged before myelosuppression in the course of chemotherapy.