Spine Metastasis of Thymic Carcinoma in a Pediatric Patient: A Case Report and Comprehensive Literature Review

Author:

Oktay KadirORCID,Guzel Ebru,Baykara Okay,Akbaba Mevlana,Sari Ibrahim,Guzel Aslan

Abstract

<b><i>Introduction:</i></b> Thymic carcinoma metastases of the spinal column are very rare, especially in pediatric patients. To our knowledge, this is the first such pediatric case in the literature. <b><i>Case Presentation:</i></b> We report the case of a 14-year-old male patient with T12 and L1 metastases of thymic carcinoma. He had history of thymectomy and intrathoracic tumor resection 7 months previously. The patient’s neurological condition deteriorated; therefore, tumor resection and decompression of the spinal canal were performed. He underwent instrumentation and fusion procedures to prevent spinal instability. <b><i>Conclusion:</i></b> The main purpose of the treatment is gross total resection of the thymic carcinoma. However, adjuvant methods such as radiotherapy and chemotherapy should be added to the treatment protocol in patients who have higher stage diseases or those in whom total tumor resection cannot be achieved.

Publisher

S. Karger AG

Subject

Neurology (clinical),General Medicine,Surgery,Pediatrics, Perinatology and Child Health

Reference11 articles.

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2. Jee TK, Lee SH, Kim HJ, Kim ES, Eoh W. Spinal metastasis of thymic carcinoma as a rare manifestation: a summary of 7 consecutive cases. Korean J Spine. 2014;11(3):157–61.

3. Liu S, Zhou X, Song A, Huo Z, Li WA, Rastogi R, et al. Surgical management of spinal metastases of thymic carcinoma: a case report and literature review. Medicine. 2019;98(3):e14198.

4. Fonseca AL, Ozgediz DE, Christison-Lagay ER, Detterbeck FC, Caty MG. Pediatric thymomas: report of two cases and comprehensive review of the literature. Pediatr Surg Int. 2014;30(3):275–86.

5. Liu T, Qiu G, Tian Y. Thymic carcinoma with primary spine metastasis. J Clin Neurosci. 2011;18(6):840–2.

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