Corneal and Conjunctival Calcification in a Dialysis Patient Reversed by Parathyroidectomy

Author:

Pessoa Maria Beatriz C.N.,Santo Ruth Miyuki,De Deus Aline A.,Duque Eduardo Jorge,Rochitte Carlos Eduardo,Moyses Rosa M.A.,Elias Rosilene M.

Abstract

Mineral and bone metabolism disorders are relatively common among patients with end-stage renal disease on maintenance hemodialysis. Corneal and conjunctival calcification is the main extravascular site for calcification. Recently, this form of calcification has been linked to vascular calcification. Secondary hyperparathyroidism can lead to high levels of calcium and phosphorus and increase the risk of calcification. Here, we report a case of a 38-year-old female with severe hyperparathyroidism who underwent eye examination before and after parathyroidectomy. Anterior segment optical coherence tomography showed an improvement in the number and size of ocular calcifications 6 months after surgery. This case calls attention to the importance of eye examination in patients on dialysis and brings the possibility of recovery of calcification in a short-term follow-up.

Publisher

S. Karger AG

Subject

Nephrology,Hematology,General Medicine

Reference2 articles.

1. Hsiao CH, Chao A, Chu SY, Lin KK, Yeung L, Lin-Tan DT, et al. Association of severity of conjunctival and corneal calcification with all-cause 1-year mortality in maintenance haemodialysis patients. Nephrol Dial Transplant. 2011 Mar;26(3):1016–23.

2. Ke G, Li S, Cui Y, Chen X, Che H, Dou C, et al. Treatment of uremic tumoral calcinosis in maintenance hemodialysis patients. Blood Purif. 2020 Apr 14:1–7.

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