Long-Lasting Complete Remission of Small-Cell Carcinoma of the Pancreas with Carboplatin and Etoposide Complicated by Gallbladder Adenocarcinoma Diagnosed during Follow-Up

Author:

Tyriakidis KonstantinosORCID,Stadlmann Sylvia,Pederiva Stefanie

Abstract

Small-cell carcinoma of the pancreas (PSCC) is a highly aggressive neoplasia with a dismal prognosis. It is extremely rare, with only a few cases reported in the literature. There is a paucity of clinical data to guide management and since the disease is mainly diagnosed at an advanced stage standard treatment consists of chemotherapy based upon treatment protocols used for small-cell lung cancer. We report the case of a female diagnosed with PSCC who achieved complete clinical remission after treatment with carboplatin and etoposide. During a 3-year follow-up the patient developed a gallbladder adenocarcinoma that was treated by surgical resection but relapsed within 20 months with widespread hematogenous metastasis.

Publisher

S. Karger AG

Subject

Oncology

Reference6 articles.

1. Ivanics T, Bergquist JR, Shubert CR, Smoot RL, Habermann EB, Truty MJ. Small cell carcinoma of the pancreas: a surgical disease. Pancreas. 2016 Nov;45(10):1461–6.

2. Ichikawa T, Federle MP, Ohba S, Ohtomo K, Sugiyama A, Fujimoto H, et al. Atypical exocrine and endocrine pancreatic tumors (anaplastic, small cell, and giant cell types): CT and pathologic features in 14 patients. Abdom Imaging. Jul-Aug 2000;25(4):409–19.

3. Sakamoto H, Kitano M, Komaki T, Noda K, Chikugo T, Kudo M. Small cell carcinoma of the pancreas: role of EUS-FNA and subsequent effective chemotherapy using carboplatin and etoposide. J Gastroenterol. 2009;44(5):432–8.

4. Morant R, Bruckner HW. Complete remission of refractory small cell carcinoma of the pancreas with cisplatin and etoposide. Cancer. 1989 Nov 15;64(10):2007–9.

5. Berkel S, Hummel F, Gaa J, Back W, Hofheinz R, Queisser W, et al. Poorly differentiated small cell carcinoma of the pancreas. A case report and review of the literature. Pancreatology. 2004;4(6):521–6.

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