Androgenetic Alopecia in a Patient with Klinefelter Syndrome: Case Report and Literature Review-Reference-Cited by-同舟云学术

Androgenetic Alopecia in a Patient with Klinefelter Syndrome: Case Report and Literature Review

Published:2020-12-07 Issue: Volume: Page:1-4
ISSN:2296-9195
Container-title:Skin Appendage Disorders
language:en
Short-container-title:Skin Appendage Disord

Author:

Alsalhi Waleed,Tosti Antonella^ORCID

Abstract

Introduction: Klinefelter syndrome (KS) is defined as (a chromosomal disorder in which males have an extra X chromosome). KS presents clinically with signs of androgen deficiency including low testosterone. Androgenetic alopecia (AGA) develops as a response of the hair follicle cells to androgens in individuals with genetic predisposition. Case Presentation: We describe a 17-year-old male patient with KS who developed AGA with a Ludwig pattern. Conclusion: Our patient had a good response to oral minoxidil, finasteride, and low-level light therapy.

Publisher

S. Karger AG

Subject

Dermatology

Reference19 articles.

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2. Barr ML. The natural history of Klinefelter’s syndrome. Fertil Steril. 1966;17(4):429–41.

3. Hamilton JB. Male hormone stimulation is a prerequisite and incitant in common baldness. J Invest Dermatol. 1942;5(6):473–4.

4. Williams GR, Franklyn JA. Physiology of the steroid-thyroid hormone nuclear receptor superfamily. Baillieres Clin Endocrinol Metab. 1994;8(2):241–66.

5. Patterson MN, McPhaul MJ, Hughes IA. Androgen insensitivity syndrome. Baillieres Clin Endocrinol Metab. 1994 Apr;8(2):379–404.

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