Skin wound healing: of players, patterns and processes

Abstract

Wound healing of the skin is a very complex biological activity. For a better understanding, an attempt is made to describe and subdivide the different players (cell types and signaling molecules), patterns (different regeneration or repair mechanisms) and processes (division of the overall process into categories, phases and steps). However, this is always based on different points of view. On the one hand, the temporality of the phases, and on the other hand, the dominant activity in each step can play a role. In addition, classifications according to wound theory and wound treatment are possible. This article aims to shed more light on the various classifications of skin wound healing and presents the underlying paradigms starting from simple approaches and ending with more detailed concepts.