AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice-Reference-Cited by-同舟云学术

AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice

Published:2019 Issue:2 Volume:180 Page:91-102
ISSN:1018-2438
Container-title:International Archives of Allergy and Immunology
language:en
Short-container-title:Int Arch Allergy Immunol

Author:

Youngblood Bradford A.,Brock Emily C.,Leung John,Falahati Rustom,Bryce Paul J.,Bright Jessica,Williams Jason,Shultz Leonard D.,Greiner Dale L.,Brehm Michael A.,Bebbington Christopher,Tomasevic Nenad

Publisher

S. Karger AG

Subject

Immunology,General Medicine,Immunology and Allergy

Reference22 articles.

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2. Kikly KK, Bochner BS, Freeman SD, Tan KB, Gallagher KT, D’alessio KJ, et al. Identification of SAF-2, a novel siglec expressed on eosinophils, mast cells, and basophils. J Allergy Clin Immunol. 2000 Jun;105(6 Pt 1):1093–100.

3. Floyd H, Ni J, Cornish AL, Zeng Z, Liu D, Carter KC, et al. Siglec-8. A novel eosinophil-specific member of the immunoglobulin superfamily. J Biol Chem. 2000 Jan;275(2):861–6.

4. Yokoi H, Choi OH, Hubbard W, Lee HS, Canning BJ, Lee HH, et al. Inhibition of FcepsilonRI-dependent mediator release and calcium flux from human mast cells by sialic acid-binding immunoglobulin-like lectin 8 engagement. J Allergy Clin Immunol. 2008 Feb;121(2):499–505.e1.

5. Nutku E, Aizawa H, Hudson SA, Bochner BS. Ligation of Siglec-8: a selective mechanism for induction of human eosinophil apoptosis. Blood. 2003 Jun;101(12):5014–20.

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