Applications of Computational Pathology in Head and Neck Cytopathology

Author:

Lollie Trang K.,Krane Jeffrey F.ORCID

Abstract

<b><i>Background:</i></b> The application of computational technology to head and neck cytology material has been explored experimentally in several areas with a variety of potential applications. <b><i>Summary:</i></b> This review summarizes the application of these techniques to the diagnosis of thyroid, salivary gland, and other head and neck fine-needle aspiration specimens. Current limitations and potential future applications in diagnosis are discussed along with the possibilities for therapeutic applications of computational methodology. <b><i>Key Message:</i></b> Particularly promising applications include resolving diagnostic uncertainty in indeterminate thyroid aspirates and assessing the tumor microenvironment in response to immunotherapy for squamous cell carcinoma.

Publisher

S. Karger AG

Subject

General Medicine,Histology,Pathology and Forensic Medicine

Reference18 articles.

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