Prevalence, Characteristics, Risk Factors, and Outcomes of Invasively Ventilated COVID-19 Patients with Acute Kidney Injury and Renal Replacement Therapy-Reference-Cited by-同舟云学术

Prevalence, Characteristics, Risk Factors, and Outcomes of Invasively Ventilated COVID-19 Patients with Acute Kidney Injury and Renal Replacement Therapy

Published:2020-07-13 Issue:1 Volume:50 Page:102-109
ISSN:0253-5068
Container-title:Blood Purification
language:en
Short-container-title:Blood Purif

Author:

Fominskiy Evgeny V.,Scandroglio Anna Mara,Monti Giacomo,Calabrò Maria Grazia,Landoni Giovanni,Dell’Acqua Antonio,Beretta Luigi,Moizo Elena,Ravizza Alfredo,Monaco Fabrizio,Campochiaro Corrado,Pieri Marina,Azzolini Maria Luisa,Borghi Giovanni,Crivellari Martina,Conte Caterina,Mattioli Cristina,Silvani Paolo,Mucci Milena,Turi Stefano,Tentori Stefano,Baiardo Redaelli Martina,Sartorelli Marianna,Angelillo Piera,Belletti Alessandro^ORCID,Nardelli Pasquale,Nisi Francesco Giuseppe,Valsecchi Gabriele,Barberio Cristina,Ciceri Fabio,Serpa Neto Ary,Dagna Lorenzo,Bellomo Rinaldo,Zangrillo Alberto,

Abstract

Background: There is no information on acute kidney injury (AKI) and continuous renal replacement therapy (CRRT) among invasively ventilated coronavirus disease 2019 (COVID-19) patients in Western healthcare systems. Objective: To study the prevalence, characteristics, risk factors and outcome of AKI and CRRT among invasively ventilated COVID-19 patients. Methods: Observational study in a tertiary care hospital in Milan, Italy. Results: Among 99 patients, 72 (75.0%) developed AKI and 17 (17.7%) received CRRT. Most of the patients developed stage 1 AKI (33 [45.8%]), while 15 (20.8%) developed stage 2 AKI and 24 (33.4%) a stage 3 AKI. Patients who developed AKI or needed CRRT at latest follow-up were older, and among CRRT treated patients a greater proportion had preexisting CKD. Hospital mortality was 38.9% for AKI and 52.9% for CRRT patients. Conclusions: Among invasively ventilated COVID-19 patients, AKI is very common and CRRT use is common. Both carry a high risk of in-hospital mortality.

Publisher

S. Karger AG

Subject

Nephrology,Hematology,General Medicine

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