The Effect of Kidney Biopsy on Glomerular Filtration Rate: A Frequent Patient Concern

Author:

Dattani Rakesh,Corbett Richard W.ORCID,Galliford Jack,Hill Peter,Cairns Tom,Cook H. Terence,Roufosse Candice,Ashby Damien R.

Abstract

The effect of percutaneous kidney biopsy on glomerular filtration rate has never been identified, though it is frequently a concern raised by patients. Following a clinical interaction with an inquisitive patient undergoing her fifth biopsy, we attempted to estimate the effect using retrospective data. In a cohort of patients with stable kidney function undergoing transplant biopsy without clinical indication (as part of a surveillance programme) the effect of biopsy was observed as a step change in glomerular filtration rate. Reassuringly, the loss of glomerular filtration rate resulting from a biopsy, has a 1-sided 95% confidence interval of <1.4 mL/min.

Publisher

S. Karger AG

Subject

Nephrology

Reference8 articles.

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