Use of CRRT and Plasmapheresis to Treat Simultaneous Iron and Acetaminophen Overdose

Author:

Nye Rebecca,Singh TriptiORCID

Abstract

There is limited information about the prevalence and treatment of concurrent acetaminophen and iron overdose. One case study has suggested that this combination may be lethal. We present a case of fatal intentional acetaminophen and iron overdose and treatment with extracorporeal methods, including continuous venovenous hemofiltration and plasmapheresis, for removal of both toxins.

Publisher

S. Karger AG

Subject

Nephrology,Hematology,General Medicine

Reference8 articles.

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3. Audimoolam VK, Wendon J, Bernal W, Heaton N, O'Grady J, Auzinger G. Iron and acetaminophen a fatal combination? Transpl Int. 2011;24(10):e85–8.

4. McGill MR, Jaeschke H. Metabolism and disposition of acetaminophen: recent advances in relation to hepatotoxicity and diagnosis. Pharm Res. 2013;30(9):2174–87.

5. Tenenbein M. Toxicokinetics and toxicodynamics of iron poisoning. Toxicol Lett. 1998;102–103:653–6.

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