Retinal Ganglion Cell Topography and Retinal Resolution in the Baikal Seal (Pusa sibirica)

Abstract

The total number, size, topographic distribution, and cell density of ganglion cells were studied in retinal wholemounts of Baikal seals (Pusa sibirica). The ganglion cell size varied from 10 to 38 μm. A distinct cell group consisted of large ganglion cells of more than 30 μm in diameter. The topographic distribution of ganglion cells showed a definite area of high cell density similar to the area centralis of terrestrial carnivores. This area was located approximately 6-7 mm dorsotemporally of the geometric center of the wholemount. In this area, the peak cell densities in two wholemounts were 3,800 and 3,400 cells/mm2 (mean 3,600 cells/mm2). With a posterior nodal distance of 24 mm (underwater), this density corresponds to 631 cells/square degree. These values predict a retinal resolution of 2.4′ in water and 3.0′ in air. The topographic distribution of large cells featured the highest density in the same location as the total ganglion cell population.