Diffuse Large B-Cell Lymphoma with Aberrant Coexpression of CD5 and CD8 T-Cell Markers

Abstract

<b><i>Introduction:</i></b> The expression of T-cell-associated antigens on diffuse large B-cell lymphoma (DLBCL) is uncommon. The coexpression of ≥2 T-cell-associated antigens on DLBCL is even rarer. This has been reported in the literature only a few times, most commonly coexpression of either CD5 or CD8 and a second, different T-cell marker. <b><i>Case Presentation:</i></b> This case report features a patient who presented with a rapidly evolving head and neck mass that displayed coexpression of CD5 and CD8. <b><i>Conclusion:</i></b> In this case report, we present the first case to our knowledge of DLBCL with coexpression of only CD5 and CD8.