For Premature Thelarche and Premature Adrenarche, the Case for Waiting before Testing

Author:

Kaplowitz Paul B.

Publisher

S. Karger AG

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism,Pediatrics, Perinatology and Child Health

Reference11 articles.

1. Kaplowitz PB, Mehra R. Clinical characteristics of children referred for signs of early puberty before age 3. J Pediatr Endocrinol Metab. 2015 Sep 1;28(9–10):1139–44.

2. De Vries L, Guz-Mark A, Lazar L, Reches A, Phillip M. Premature thelarche: age at presentation affects clinical course but not clinical characteristics or risk to progress to precocious puberty. J Pediatr. 2010;156(3):466–71.

3. Bizzarri C, Spadoni GL, Bottaro G, Montanari G, Giannone G, Cappa M, et al. The response to gonadotropin releasing hormone (GnRH) stimulation test does not predict the progression to true precocious puberty in girls with onset of premature thelarche in the first three years of life. J Clin Endocrinol Metab. 2014;99(2):433–9.

4. Novello L, Speiser PW. Premature adrenarche. Pediatr Ann. 2018 Jan 1;47(1):e7–11.

5. Paris F, Kalfa N, Philibert P, Jeandel C, Gaspari L, Sultan C. Very premature pubarche in girls is not a pubertal variant. Hormones. 2012 Jul–Sep;11(3):356–60.

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1. Precocious Puberty: Types, Pathogenesis and Updated Management;Cureus;2023-10-22

2. Premature thelarche: An Updated Review;Current Pediatric Reviews;2023-07-26

3. Early Puberty;Pediatrics In Review;2022-09-01

4. Normal and Premature Adrenarche;Endocrine Reviews;2021-03-31

5. Diagnosis and management of precocious sexual maturation: an updated review;European Journal of Pediatrics;2021-03-21

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