Squamous Cell Carcinoma Arising in Ungual Lichen Planus: Report and Review

Abstract

<b><i>Background:</i></b> Lichen planus (LP) can lead to severe scarring of the nail unit leading to anonychia. There are very few reports of squamous cell carcinoma (SCC) occurring in the lesions of ungual LP. <b><i>Objective:</i></b> The aim of this study was to revise the previously reported cases of SCC appearing in ungual LP and to present a new case. <b><i>Methods:</i></b> A PubMed search was performed with the terms “nail lichen planus” and “squamous cell carcinoma.” Reported cases as well as a new case were depicted in a table. <b><i>Results:</i></b> Only 2 indexed articles reporting 3 cases were found. All patients suffered of long-lasting scarring ungual LP. <b><i>Conclusions:</i></b> The occurrence of SCC in nail LP is rare. LP is not “premalignant” per se, but SCC might rarely arise in LP scars.