Acute Myeloid Leukemia Presenting as a Cardiac Mass

Author:

Magzoub Mohamed Alia,Saleh Maysa,Alzarawani Fatima,El-kholy Nermeen

Abstract

Leukemias are the most common childhood malignancy. It is a systemic disease presenting with different signs and symptoms. Extramedullary manifestations, in particular myeloid sarcoma (MS), are extremely rare, often challenging to identify, even more challenging to diagnose, and more than often misdiagnosed owing to its similarity with other solid tumors. We describe a previously healthy boy, aged 4 years, who had a cardiac mass lesion, presumed to be a MS, noted in the right atrium at the time of initial routine echocardiography. The lesion resolved without surgical intervention following the institution of multi-agent chemotherapy.

Publisher

S. Karger AG

Reference15 articles.

1. Kashofer K, Gornicec M, Lind K, Caraffini V, Schauer S, Beham-Schmid C, et al. Detection of prognostically relevant mutations and translocations in myeloid sarcoma by next generation sequencing. Leuk Lymphoma. 2018 Feb 1;59(2):501–4.

2. Wang HQ, Li J. Clinicopathological features of myeloid sarcoma: report of 39 cases and literature review. Pathol Res Pract. 2016 Sep 1;212(9):817–24.

3. Vardiman JW. The World Health Organization (WHO) classification of tumors of the hematopoietic and lymphoid tissues: an overview with emphasis on the myeloid neoplasms. Chem Biol Interact. 2010 Mar 19;184(1–2):16–20.

4. Ohanian M, Faderl S, Ravandi F, Pemmaraju N, Garcia-Manero G, Cortes J, et al. Is acute myeloid leukemia a liquid tumor? Int J Cancer. 2013 Aug 1;133(3):534–43.

5. Tsimberidou AM, Kantarjian HM, Wen S, Keating MJ, O’Brien S, Brandt M, et al. Myeloid sarcoma is associated with superior event‐free survival and overall survival compared with acute myeloid leukemia. Cancer. 2008 Sep 15;113(6):1370–8.

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