Gentamicin should remain part of the empirical sepsis regimen for adults

Author:

Grønmo Maria Mellemstrand,Møller-Stray Janne,Akselsen Per Espen,Lindemann Paul Christoffer,Fostervold Aasmund,Knudsen Caroline Vestby,Knudsen Per Kristian,Lindbæk Morten,Tonby Kristian,Sundsfjord Arnfinn

Publisher

Norwegian Medical Association

Reference24 articles.

1. Helsedirektoratet. Nasjonal faglig retningslinje for antibiotika i sykehus. https://www.helsedirektoratet.no/retningslinjer/antibiotika-i-sykehus Lest 3.1.2024.

2. Paul M, Lador A, Grozinsky-Glasberg S et al. Beta lactam antibiotic monotherapy versus beta lactam-aminoglycoside antibiotic combination therapy for sepsis. Cochrane Database Syst Rev 2014; 2014: CD003344. [PubMed][CrossRef]

3. Sæterdal I, Holte HH, Harboe I et al. Effect of Using Aminoglycosides for Treatment of Sepsis. https://www.fhi.no/globalassets/dokumenterfiler/rapporter/2015/rapport_2015_3_aminoglycosider.pdf Lest 3.1.2024.

4. Carlsen S, Boel J, Jarløv JO et al. The effect of short-course gentamicin therapy on kidney function in patients with bacteraemia-a retrospective cohort study. Eur J Clin Microbiol Infect Dis 2018; 37: 2307–12. [PubMed][CrossRef]

5. Cobussen M, de Kort JML, Dennert RM et al. No increased risk of acute kidney injury after a single dose of gentamicin in patients with sepsis. Infect Dis (Lond) 2016; 48: 274–80. [PubMed][CrossRef]

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