Affiliation:
1. Dr.Ersin Arslan Education and Research Hospital
2. Kırıkkale Yuksek Ihtisas Hospital
3. KIRIKKALE UNIVERSITY
4. Kahramanmaras Sutcu Imam University
5. Kepez State Hospital
Abstract
Aim: Several studies have investigated the association between biomarkers and short-term prognosis in the coronavirus infectious disease 2019 (COVID-19). However, data on the long-term prognosis are limited. To determine the predictive value of systemic immune-inflammation index (SII) and C-reactive protein (CRP) to albumin ratio (CAR) for in-hospital and 1-year outcomes during COVID-19.
Material and Method: The primary outcomes were in-hospital and 1-year mortality. The secondary outcomes were the intensive care unit (ICU) need at admission and transfer to the ICU later on.
Results: The study included 449 (53.6%) males and 389 (46.4%) females with a mean age of 53.8±18.5 years. Previously known heart failure (HF), COVID-19-related HF, acute renal failure (ARF), diabetes mellitus, hypertension, coronary artery disease (CAD), chronic obstructive pulmonary disease (COPD)/asthma, high CO-RADS scores (>4), low ejection fraction (EF), higher CAR and SII were associated with an increased in-hospital and 1-year mortality (p
Publisher
Journal of Medicine and Palliative Care
Reference27 articles.
1. Virani SS, Alonso A, Aparicio HJ, et al. Heart Disease and Stroke Statistics-2021 update: a report from the American Heart Association. Circulation 2021; 143: e254-743.
2. Piombi-Adanza SN, Baretto MC, Echaide FA, et al. Analysis of oxygen blood saturation/respiratory rate index, NEWS2, CURB65, and quick sequential organ failure assessment scores to assess prognosis in patients with mild coronavirus disease 2019. Rev Invest Clin 2021; 73: 399-407.
3. Inanc IH, Bursa N, Gultepe A, Bayramoğlu M, Sabanoglu C, Inanc FA. Association among CO-RADS score, co-morbid diseases, and short-term prognosis in COVID-19 infection. Eur Rev Med Pharmacol Sci 2022; 26: 653-63.
4. Gaspar-Hernández J, Araiza-Garaygordobil D, Gopar-Nieto R, Martínez-Amezcua P, Arias-Mendoza A. impact of the coronavirus disease-19 pandemic on acute cardiovascular emergencies in a third level cardiology hospital: a call for action. Rev Invest Clin 2020; 72: 280-2.
5. Ramos-Araque ME, Siegler JE, Ribo M, et al. Stroke etiologies in patients with COVID-19: the SVIN COVID-19 multinational registry. BMC Neurol 2021; 21: 43.