COMBINED THERAPY WITH MEDICAL GASES AND RESPIRATORY SUPPORT IN PATIENTS WITH HYPERCAPNIC RESPIRATORY FAILURE WITH EXACERBATION OF COPD

Abstract

COPD is one of the leading causes of morbidity and mortality in the Russian Federation. The prevalence reaches 6-10% of the general population. Severe and frequent exacerbations of COPD lead to acute hypercapnic DN requiring NIV. In 30% of patients with severe exacerbation of COPD, NIV does not lead to the desired results. To optimize NIV in this group of patients, we used inhalations of thermal heliox (t-He/O2) and nitric oxide (iNO), which significantly improved O2 transport, CO2 elimination, hemodynamics and stabilized lactate levels.