A meta-analysis on the use of photobiomodulation to regulate gingival wound healing in addition to periodontal therapies

Author:

Koang Yaieo1

Affiliation:

1. Department of Stomatology, Xinxeiang Central Hospital, The Fourth Clinical College of Xinxeiang Medical University, Henan, 453000, China

Abstract

<p class="MsoNormal"><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi; background: white;">Background:</span></p> <p class="MsoNormal"><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi; background: white;">A meta-analysis research was implemented to appraise </span><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi;">gingival wound healing management by photobiomodulation as adjunctive management to periodontal treatments<span style="background: white;">.</span></span></p> <p class="MsoNormal"><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi;">Inclusive literature research till April 2023 was done and 908 interconnected researches were revised. Methods</span></p> <p class="MsoNormal"><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi;">The 9 picked researches, enclosed 517 periodontal disease persons were in the utilized researchers' starting point, 258 of them were utilizing photobiomodulation</span><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi; mso-bidi-language: AR-EG;">,</span><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi;"> and 259 were control. </span><span lang="EN-GB" style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi; mso-ansi-language: EN-GB;">Odds ratio (OR)</span><span lang="EN-GB" style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi;"> </span><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi;">and 95% confidence intervals (CIs) were utilized </span><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi;">to </span><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi; background: white;">appraise </span><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi;">the consequence of photobiomodulation in treating gingival wound healing</span><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi;"> by the </span><span lang="EN-GB" style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi; mso-ansi-language: EN-GB;">dichotomous</span><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi; mso-bidi-language: AR-EG;">, and contentious approach</span><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi;"> and a fixed or random model. </span></p> <p class="MsoNormal"><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi; mso-bidi-language: AR-EG;">Results:</span></p> <p class="MsoNormal"><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi; mso-bidi-language: AR-EG;">Photobiomodulation </span><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi;">had a significantly higher Landry wound healing index (MD, 0.87; 95% CI, 0.40-1.34, p&lt;0.001), and complete wound epithelialization (OR, 6.47; 95% CI, 2.05-20.44, p=0.001) compared to the </span><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi; mso-bidi-language: AR-EG;">control of gingival wound healing in periodontal disease persons</span><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi;">. However, </span><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi; mso-bidi-language: AR-EG;">photobiomodulation and control</span><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi;"> had no significant difference in the remaining wound area (MD, -10.03; 95% CI, -22.83-2.77, p=0.12) </span><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi; mso-bidi-language: AR-EG;">of gingival wound healing in periodontal disease persons</span><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi;">.</span></p> <p class="MsoNormal"><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi; mso-bidi-language: AR-EG;">Conclusions:</span></p> <p class="MsoNormal"><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi; mso-bidi-language: AR-EG;">Photobiomodulation </span><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi;">had a significantly higher Landry wound healing index, and complete wound epithelialization, however, no significant difference was found in the remaining wound area compared to </span><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi; mso-bidi-language: AR-EG;">control of gingival wound healing in periodontal disease persons</span><span style="font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi;">. However, caution needs to be taken when interacting with its values since there was a low sample size of most of the chosen research found for the comparisons in the meta-analysis and a low number of chosen investigations for some of the comparisons.</span></p>

Publisher

Pharaoh Academy International Publishing Co., Limited

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