Evaluation of Vitamin D3 in Thyroid Disorder Iraqi Women (Hypothyroidism with and without Metabolic Syndrome)

Abstract

This study was designed to evaluate vitamin D3 and metabolic hormones in hypothyroidism with metabolic syndrome and hypothyroidism without metabolic syndrome. Sixty patients with hypothyroidism were divided into three groups, 30 with hypothyroidism with metabolic syndrome, 30 with hypothyroidism without metabolic syndrome, and 30 with healthy controls compared with the patients. There was a significant increase in tetraiodothyronine, free thyronine and a very significant increase in thyroid stimulating hormone in women with hypothyroidism with metabolic syndrome compared to women with hypothyroidism without metabolic syndrome. A significant increase in systolic blood pressure, body mass index, fasting blood glucose, glycosylated hemoglobin, insulin resistance, high-density lipoproteins, triglycerides and vitamin D3 in women with hypothyroidism with metabolic syndrome compared to women with hypothyroidism without metabolic syndrome. It can be concluded that a deficiency in the vitamin D level in the body negatively affects the various functions of the immune system, which increases the likelihood of developing severe immune diseases attacking the thyroid gland in diabetic women with metabolic syndrome. Keywords: Hypothyroidism, Metabolic Syndrome, Vitamin D3, Insulin Resistance