Determination of IFN-y in Patients with Pseudomonas aeruginosa-Inflicted Burn and Wound

Abstract

The sample collection was carried out from 1/12/2021 to 1/4/2022 at the burns hospital, Baghdad teaching hospital in Baghdad city, and Alhussain teaching hospital in Almuthana city. Samples were collected from patients' sera collection samples from (69) patients, from burn patients 53 and 16 samples from wound patients infected with pseudomonas aeruginosa; 41 patients were males, and 28 were females. This group used the other 69 patients that were not infected by bacteria as a control group. The level of IFN-y was investigated by ELISA assay in the teaching Laboratories in al Sawawah city. The results showed a decrease in IFN-y levels were 35.2±2.6 for burn patients and 35.4±2.3 for wound patients compared to the control group of 46±2.5. The current study reported a highly significant difference in IFN-y levels between the burn and wound patients and the control group (P<0.0001 ). Keywords: Pseudomonas aeruginosa; Burn; wound; Interferon – Gamma.