Affiliation:
1. Department of Chemistry / College of Education for Pure Science (Ibn-Al-Haitham), the University of Baghdad, Iraq.
Abstract
In this research, new compounds were synthesized via the reaction of dichloroacetic acid with two moles of piperidine. The novel acid 1 was converted to its ester
2. Acid hydrizide 3 was prepared by the reaction of hydrazine hydrate with new
ester 2, which was later used to prepare derivatives of Schiff bases 4-13. In the last
step, Schiff bases and thioglycolic acid were reacted to give thiazolidine derivatives 14-23. All these compounds were diagnosed using melting points, FTIR,
1HNMR and mass spectroscopy. Scheme 1 shows all the synthesized compounds'
reaction steps and structures.
Keywords: Thiazolidine; Schiff bases; biological activity; piperidine; dichloroacetic acid.
Subject
Infectious Diseases,Applied Microbiology and Biotechnology,Epidemiology,Biotechnology
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