The role of serotonin, acetylcholine, nitric oxide and FMRF-amide in the adaptation of scallops to hypoxia

Author:

Kotsyuba E. P.1ORCID,Dyachuk V. A.1

Affiliation:

1. A.V. Zhirmunsky National Scientific Center of Marine Biology, Far Eastern Branch, Russian Academy of Sciences

Abstract

The problem of adaptation to oxygen deficiency and its role in the development of diseases have been studied for many decades on animal models having different level of resistance to hypoxia. This review discusses the literature data and the results of our own studies of hormonal and mediator systems of the central nervous system, as well as the clarification of their role in adaptive physiological and behavioral reactions in bivalves. The analysis of data on serotonin topography  (5-HT), acetylcholine (ACh), nitric oxide (NO) and FMRF-amide-containing neurons in the visceral ganglion and the dynamics of their activity provides evidence of the participation of neurotransmitters and enzymes of their synthesis in the stability and plasticity of the nervous system of scallops suffering hypoxia.

Publisher

Pacific State Medical University

Subject

General Medicine

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