Pituicytoma: A clinical case of hormonally inactive pituitary macroadenoma with chiasma compression

Abstract

In the article, a clinical case of a hormonally inactive tumor of the posterior pituitary is described. The clinical symptoms were caused by mass effect (chiasma compression and hypopituitarism). Transnasal transsphenoidal adenomectomy was performed on the patient. Subsequent morphologic examination revealed a solid neoplasm of large cells with broad oxyphilic granular cytoplasm, presumably originating from adenohypophysis cells. By immunohistochemical examination, pituicytoma, a granular cell tumor of the posterior pituitary, was diagnosed. Hence, the significance of differential diagnostics of pituicytoma is indicated, including clinical and hormonal manifestations, as well as pathomorphologic analysis data.