Comorbidity structure in psoriasis patients according to dermatology department data

Abstract

Aim. An analysis of the structure of concomitant pathology in patients with widespread psoriasis vulgaris.Materials and methods. An open, uncontrolled, single-center retrospective study of the case histories of 100 patients with widespread plaque psoriasis who received medical care in a dermatology department of Irkutsk State Medical University clinics was carried out. Concomitant pathology was established on the basis of anamnesis and physical examination, as well as laboratory tests and consultations with a physician and related specialists.Results. Diseases of the gastrointestinal tract accounted for 81%, of which non-alcoholic fatty liver disease was detected in 43%. Endocrinopathies were noted in 72% of patients, a third (30%) had obesity of varying degrees, and 14% had type 2 diabetes mellitus. Pathologies of the circulatory system was diagnosed in 34% of patients, including hypertension in 29%. Psoriatic arthritis was detected in 11% of cases. In patients under 40 years of age, an average of 1–2 comorbid conditions were noted, while the number of concomitant diseases increased to 4–5 by the age of 60. Only 17% of the patients had no comorbidities.Conclusions. In the majority of patients, psoriasis is associated with certain diseases, being a harbinger of their development. This fact should be taken into account when determining personalized treatment tactics.