Factors Influencing Kanamycin Resistance in Gram-Negative Enteric Neonatal Sepsis

Author:

Crosson Francis J.1,Moxon E. Richard1

Affiliation:

1. Division of Infectious Diseases, Department of Pediatrics, The Johns Hopkins University Hospital Baltimore, MD 21205

Abstract

Gram-negative enteric organisms are responsible for at least 50% of cases of neonatal septicemia.1,2 Because of the emergence of kanamycin-resistant organisms, gentamicin has become the aminoglycoside agent of choice in many neonatal intensive care units.1 Increased use of gentamicin, however, favors the development of gentamicin resistance,3 which has prompted interest in reducing reliance on gentamicin. Baker et al.4 have suggested that the incidence of kanamycin resistance among Escherichia coli isolates from neonates is low if illness begins during the first few days of life but is greater among isolates from infants with illnesses of later onset. They demonstrated a correlation between pretreatment with kanamycin and subsequent recovery of kanamycin-resistant organisms from these same infants.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology and Child Health

Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3